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Table 1 Antimicrobial resistance profiles of ESBL-EC isolates from Humans, chickens and farm/market environments in Abuja - Nigeria, 2019

From: Extended-spectrum ß-lactamase-producing Escherichia coli among humans, chickens and poultry environments in Abuja, Nigeria

Drug ClassDrugMIC Resistance breakpoint μg/mLHumans,
n = 14
(%)
Chickens n = 14
(%)
Environment
n = 9
(%)
TetracyclinesTetracyclines (TET)≥ 1614 (100)13 (92.9)9 (100)
Folate Pathway antagonistsSulfamethoxazole Trimethoprim (SXT)≥ 4/7612 (85.7)10 (71.4)9 (100)
Sulfisoxazole (FIS)≥51212 (85.7)9 (64.3)9 (100)
PenicillinsAmpicillin (AMP)≥ 3213 (92.9)14 (100)9 (100)
QuinolonesNalidixic acid (NAL)≥ 325 (35.7)7 (50.00)5 (55.6)
Ciprofloxacin (CIP)≥ 43 (21.4)5 (35.7)2 (22.2)
AminoglycosidesStreptomycin (STR)≥ 3210 (71.4)10 (71.4)8 (88.9)
Gentamicin (GEN)≥ 165 (35.7)7 (50.00)5 (55.6)
PhenicolsChloramphenicol (CHL)≥ 323 (21.4)7 (50.00)2 (22.2)
Macrolide AntibioticsAzithromycin (AZI)≥ 324 (28.6)4 (28.6)5 (55.6)
B-lactam inhibitorsAmoxicillin-clavulanate (AMC)≥ 32/161 (7.14)0 (0)0 (0)
CephemCeftriaxone (CRO)≥ 42 (14.3)2 (14.3)0 (0)
Cefoxitin (FOX)≥ 3214 (100)14 (100)1 (11.1)
Ceftiofur (XNL)≥ 82 (14.3)2 (14.3)1 (11.1)
Resistance to 3 or more classes of antibioticsMDRn/a13 (92.9)13 (92.9)9 (100)