From: Make science evolve into a One Health approach to improve health and security: a white paper
1. | Burden and Impact of AMR  - AMR and global burden of disease  - Global health security  - Impact of AMR on animal production and food safety  - Impact of AMR on global trade  - Societal impacts from AMR  - Economic impact |
2. | Transmission human, animal, environment  - What has been achieved, what is the evidence?  - Systems epidemiology of transmission  - Biosafety  - Farm to fork to man and back?  - Waste management and impact on AMR transmission |
3. | Surveillance of AMR  - Human (hospital, community), animal, environment  - Use of whole genome sequencing for surveillance, one health microbiology, Global Microbial Identifier  - Evolution of AMR  - Gene mobilization factors (including waste management)  - Integrated AMR and antimicrobial use surveillance  - Big data |
4. | Use of antibiotics  - AMR and use of antibiotics for growth promotion  - Role of antibiotics (including food safety)  - Antimicrobial treatment of emerging MDROs  - Antimicrobial stewardship  - Infection prevention and control  - Access to antimicrobial medicines  - Quality of antibiotics |
5. | Policy interventions  - Global policy interventions, IACG  - National Action Plans  - National/regional experience in reducing antimicrobial use: Efficiency and Effect  - AMR and SDGs  - Regulatory interventions  - Use of Big Data to guide interventions  - Trade policy (impact on global trade)  - Quality measures of antibiotics |
6. | New economic models  - Push/pull incentives for antibiotic drug and diagnostic development  - Public private partnerships  - Drug/Diagnostic partnerships  - Economic impact assessment and modelling  - Economic benefits  - New models of trade |
7. | Behaviour Change and Social Sciences  - Antimicrobial stewardship  - Public perception and education in all One Health sectors  - Socioeconomic barriers and cultural differences  - Consumer behaviour and pressure  - Serious gaming  - Design thinking |
8. | Capacity building  - Training the next generation  - Building surveillance infrastructure  - Implementation National Action Plans  - One health approaches to teaching and training curricula |
9. | Diagnostics and detection  - Rapid, point of care, pen side diagnostics  - Outbreak detection  - Biomarkers of infection  - Food safety and monitoring  - Diagnostic stewardship |
10. | Antibiotic drug development and manufacturing  - Design and implementation of efficient clinical trials for novel antibiotics  - Development of new antimicrobials  - Addressing bacterial cell wall permeability  - Manufacturing in LMICS  - Waste/waste water treatment |
11. | Alternative approaches to tackling resistant infections  - Vaccines (against bacteria, viruses, etc)  - Antibiotic alternatives (e.g. bacteriophages, immune modulators)  - Non-traditional approaches for humans and animals  - Genome editing  - Animal models of disease |